Ethyl Pyruvate

Ethyl Pyruvate is a versatile alpha-keto ester derived from pyruvic acid, widely used as an organic synthesis intermediate and in biochemical research.

Appearance:
Colorless to light yellow transparent liquid
CAS No.:
617-35-6
Molecular Formula:
C5H8O3
Molecular Weight:
116.12
EINECS:
210-511-2
Solubility:
Slightly soluble in water

Availability:



Inquiry Add to Basket

Product Description

Product Description

Ethyl Pyruvate is a versatile alpha-keto ester derived from pyruvic acid, widely used as an organic synthesis intermediate and in biochemical research. This stable, lipophilic compound exhibits antioxidant and anti-inflammatory properties, making it a valuable reagent in pharmaceutical development, flavor formulation, and advanced research applications.

Technical Specification

ITEMS	SPECIFICATIONS
Appearance	Colorless to light yellow transparent liquid
Purity (By GC)	≥98.0%
Water	≤0.5%

Packaging and Storage

Net weight 200kgs plastic drum, 16MT/FCL with pallets.
Store at cool dry place, keep away form light. Protect from moisture and prolonged exposure to air.

Key Features and Benefits

Antioxidant Activity:

Effectively neutralizes ROS, protecting cells from oxidative damage.

Anti-Inflammatory Properties:

Modulates inflammatory pathways, showing promise in studies of sepsis, ischemia-reperfusion injury, and neuroinflammation.

Versatile Intermediate:

Essential in organic synthesis for pharmaceuticals, agrochemicals, and heterocyclic compounds.

Food-Grade Applications:

Used as a flavoring agent (FEMA 2457) in apples, citrus, and chocolate formulations, with GRAS status in limited quantities.

Research-Backed:

Extensively studied in animal models for organ protection (heart, liver, kidney, brain) and potential therapeutic roles in conditions like acute pancreatitis, stroke, and arthritis.

Applications of Ethyl Pyruvate

Pharmaceutical Research:

Investigated for neuroprotective, anti-inflammatory, and organ-protective effects in models of ischemia-reperfusion injury, sepsis, acute respiratory distress syndrome (ARDS), and neurodegenerative diseases.

Organic Synthesis:

Key building block for synthesizing BACE-1 inhibitors (Alzheimer's research), thiophene derivatives, and other bioactive compounds.

Food and Flavor Industry:

Enhances fruity notes in beverages, candies, and baked goods; acts as a preservative.

Biotechnology:

Supports fermentation processes and biofuel production.

Cosmetics:

Inhibits tyrosinase for skin-brightening effects and serves as an air freshener component to neutralize odors.

Frequently Asked Questions (FAQs)

Q: What is Ethyl Pyruvate?

A: Ethyl Pyruvate is the ethyl ester of pyruvic acid, a simple aliphatic compound (C₅H₈O₃) known for its antioxidant and anti-inflammatory properties. It is more stable and lipophilic than pyruvate salts.

Q: What are the primary uses of Ethyl Pyruvate?

A: It is primarily used in organic synthesis, pharmaceutical research (anti-inflammatory studies), flavoring (food industry), and as a research tool for oxidative stress and inflammation models.

Q: What is the difference between Ethyl Pyruvate and Sodium Pyruvate?

A: Ethyl Pyruvate is more lipophilic, allowing better cellular uptake and greater stability in solutions. It often shows enhanced antioxidant and anti-inflammatory effects compared to sodium pyruvate.

Q: Can Ethyl Pyruvate be used in food products?

A: Yes, as a flavoring agent (FEMA 2457) in beverages, candies, and baked goods, typically at levels of 20-150 ppm depending on the application.

Q: Is Ethyl Pyruvate flammable?

A: Yes, it is a flammable liquid. Keep away from open flames and store appropriately.