Methyl Pyruvate

Methyl Pyruvate (CAS 600-22-6) is a highly reactive α-keto ester widely used as a versatile building block in organic synthesis and pharmaceutical intermediates.

Appearance:
Colorless to light yellow transparent liquid
CAS No.:
600-22-6
Molecular Formula:
C4H6O3
Molecular Weight:
102.09
EINECS:
209-987-4
Solubility:
Slightly soluble in water

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Product Description

Product Description

Methyl Pyruvate (CAS 600-22-6) is a highly reactive α-keto ester widely used as a versatile building block in organic synthesis and pharmaceutical intermediates. It contains both ketone and ester functional groups in the same molecule, enabling diverse chemical transformations such as aldol reactions, Michael additions, reductive aminations, and heterocyclic synthesis.

This premium-grade methyl pyruvate is manufactured under strict quality control and is suitable for research and development, pharmaceutical intermediates, agrochemical synthesis, flavor & fragrance applications, and academic laboratories.

Technical Specification

ITEMS	SPECIFICATIONS
Appearance	Colorless to light yellow transparent liquid
Purity (By GC)	≥98.0%
Water	≤0.5%

Packaging and Storage

Net weight 200kgs plastic drum, 16MT/FCL with pallets.
Store at cool dry place, keep away form light. Protect from moisture and prolonged exposure to air.

Applications of Methyl Pyruvate

Pharmaceutical intermediates: precursor for statins, antiviral drugs, and amino acid synthesis.
Peptide synthesis: protecting group and chiral building block.
Flavor and fragrance: imparts caramel, ethereal, and fruity notes (FEMA 2673).
Agrochemical synthesis: key intermediate for modern pesticides and herbicides.
Biochemical research: substrate for enzyme studies and metabolic pathway research.
Organic synthesis: versatile reagent for aldol reactions, Michael additions, and heterocyclic compound synthesis.

Frequently Asked Questions (FAQs)

Q: What is Methyl Pyruvate used for?

A: Methyl Pyruvate is primarily used as a pharmaceutical intermediate (e.g., in statin and antiviral drug synthesis), a flavoring agent with caramel-like notes, and a versatile building block in organic and peptide synthesis.

Q: Is Methyl Pyruvate the same as Ethyl Pyruvate?

A: No. Methyl Pyruvate (CAS 600-22-6) is the methyl ester, while Ethyl Pyruvate (CAS 617-35-6) is the ethyl ester. They have similar reactivity but different physical properties and regulatory approvals.

Q: Does methyl pyruvate polymerize or degrade over time?

A: Methyl pyruvate is relatively stable when stored properly at 2–8 °C under nitrogen. It can slowly undergo self-aldol condensation if exposed to moisture or basic impurities. Always use fresh material for critical reactions.

Q: Can methyl pyruvate be used in flavor formulations?

A: Yes. It is FEMA GRAS (No. 2673) and widely used to impart buttery, caramel notes in food and beverage applications at typical use levels of 1–20 ppm.