Disodium Succinate Anhydrous | Food and Specialty Grade Supplier

Disodium Succinate Anhydrous at a Glance

Disodium Succinate Anhydrous is the anhydrous disodium salt of succinic acid. It is a white to off-white, water-soluble crystalline powder identified by CAS No. 150-90-3.

It is used as a savory flavor ingredient, flavor enhancer, acidity regulator, buffer component, laboratory reagent and raw material for selected biotechnology, fermentation and pharmaceutical processes. Food use is subject to the regulations of the destination market and requires an appropriately qualified food-grade product.

We supply Disodium Succinate Anhydrous against agreed purity, moisture, impurity, particle-size, microbiological and documentation requirements. Final specifications are confirmed in the quotation and batch Certificate of Analysis.

• Product name: Disodium Succinate Anhydrous

• Alternative name: Sodium Succinate Anhydrous

• Chemical name: Succinic Acid Disodium Salt

• IUPAC name: Disodium Butanedioate

• CAS number: 150-90-3

• EC number: 205-778-7

• Molecular formula: C₄H₄Na₂O₄

• Molecular weight: 162.05 g/mol

• FEMA number: 3277

• Related INS designation: 364(ii)

• Appearance: White to off-white crystalline powder

• Chemical type: Organic acid salt

• Primary commercial role: Fine chemical and functional ingredient

Chemical Identity and Reference Properties

These values are general identification information. The applicable specification and Certificate of Analysis should be used for batch acceptance.

Anhydrous vs Hexahydrate Disodium Succinate

Disodium Succinate is commercially available in anhydrous and hexahydrate forms. They have different molecular weights, water contents and active-material concentrations.

The theoretical anhydrous fraction of the hexahydrate is approximately 60% by weight. Therefore, the two forms should not be substituted on a one-to-one weight basis.

Any conversion must also account for the actual assay and moisture shown on the Certificate of Analysis.

Why the Water Form Matters

Selecting the wrong hydration form can affect:

• Ingredient dosage

• Flavor intensity

• Sodium contribution

• Dry-blend moisture

• Powder flow

• Dissolution behavior

• Product yield

• Cost per unit of active succinate

• Label and specification compliance

An RFQ should always state “anhydrous” or “hexahydrate,” not only “Disodium Succinate.”

Available Disodium Succinate Grades

Food Grade Disodium Succinate

Food-grade Disodium Succinate Anhydrous is produced and controlled for use as a flavoring substance, flavor enhancer or acidity-regulating ingredient where permitted.

Important purchasing criteria may include:

• Assay

• Loss on drying

• Chloride

• Sulfate

• Heavy metals

• Lead and arsenic

• Solution clarity

• pH

• Particle size

• Microbiological limits

• Allergen and GMO documentation

• Kosher or Halal certification

• Regulatory status in the destination market

Food-grade status must be supported by appropriate manufacturing controls and documentation. A reagent or industrial product should not be used in food solely because it has a high assay.

Pharmaceutical or NF Grade

Appropriately qualified Sodium Succinate may be used as a pharmaceutical excipient, buffer component or process material.

Depending on the application, buyers may require:

• USP/NF or other compendial compliance

• Defined assay and water content

• Elemental-impurity data

• Microbiological limits

• Bacterial endotoxin limits

• GMP documentation

• Change-control commitments

• Batch traceability

• Intended-use labeling

A general food or reagent grade must not automatically be represented as pharmaceutical grade.

Low-Endotoxin Bioprocess Grade

Low-endotoxin material may be selected for culture-media preparation, bioprocess buffers and other applications in which endotoxin control is important.

The specification should state the actual endotoxin limit and analytical method. The expression “low endotoxin” has little procurement value without a numerical limit.

Reagent and Synthesis Grade

Reagent-grade Disodium Succinate Anhydrous is used in laboratory synthesis, analytical chemistry, buffer preparation and research.

Relevant parameters may include:

• Assay

• Infrared identification

• Loss on drying

• Insoluble matter

• pH

• Trace metals

• Chloride

• Sulfate

• Lot-specific analytical documentation

Reagent grade does not establish food or pharmaceutical suitability.

Industrial and Technical Grade

Industrial material may be used in chemical processing, fermentation, electroplating, specialty formulations or as an intermediate for other succinate products.

Industrial grades can have broader impurity limits and are not interchangeable with food or pharmaceutical grades.

Typical Quality Parameters

Numerical limits should be tied to a defined test method. Results from different methods or reporting bases may not be directly comparable.

How Disodium Succinate Supports Savory Flavor

Food-grade Disodium Succinate contributes a characteristic salty, savory and umami-like taste profile. It is often used to increase flavor depth rather than to provide a dominant standalone taste.

Depending on the formulation, it may:

• Enhance savory impact

• Increase broth-like fullness

• Support meaty or seafood flavor notes

• Improve flavor persistence

• Complement glutamate-based seasonings

• Complement nucleotide flavor enhancers

• Strengthen salt perception

• Round acidic or thin flavor profiles

• Improve the mouthfeel of selected beverages or liquid flavors

The optimum concentration depends on the food matrix, salt level, pH and other flavor ingredients. Finished-product sensory testing is essential.

Disodium Succinate Anhydrous Applications

Disodium Succinate Anhydrous is used as a functional ingredient in food, laboratory, biotechnology and specialty chemical systems.

Savory Seasonings and Dry Blends

The anhydrous form is well suited to dry seasoning systems because it provides higher active succinate content with no water of crystallization.

Potential applications include:

• Compound seasonings

• Soup and broth powders

• Instant noodle seasonings

• Savory snack coatings

• Meat seasonings

• Seafood seasonings

• Sauce and gravy mixes

• Bouillon products

• Plant-based savory flavors

• Salt-reduction flavor systems

Particle-size compatibility should be evaluated to reduce segregation during transport and blending.

Sauces, Soups and Liquid Foods

Disodium Succinate can be dissolved into liquid flavor systems, sauces, soup bases, marinades and brines where permitted.

Formulators should evaluate:

• Dissolution sequence

• Final pH

• Sodium contribution

• Interaction with glutamates and nucleotides

• Flavor intensity

• Heat processing

• Shelf-life stability

• Local additive or flavoring regulations

Flavor and Fragrance Compounding

Disodium Succinate Anhydrous may be used as a flavor substance or functional component in savory flavor systems.

For flavor-house qualification, buyers may request FEMA identification, flavoring-status documentation, natural-origin documentation where applicable and destination-market regulatory support.

A “natural” claim depends on the production process and market definition; it cannot be inferred from the chemical name alone.

Buffer and pH-Control Systems

As the disodium salt of a dicarboxylic acid, Sodium Succinate can be used in succinate buffer systems.

Buffer performance depends on:

• Succinic acid-to-succinate ratio

• Target pH

• Solution concentration

• Temperature

• Ionic strength

• Other formulation components

Disodium Succinate alone is not a complete guarantee of a specific buffer pH. The required acid/base ratio must be developed for the application.

Fermentation and Biotechnology

Succinate salts may serve as carbon-source components, media ingredients, pH-control materials or metabolic intermediates in selected microbial and cell-based processes.

Suitable applications may include:

• Fermentation-media preparation

• Culture-media formulation

• Biocatalysis

• Enzyme processes

• Biochemical research

• Downstream process buffers

• Process-development studies

The required grade may involve tighter trace-metal, microbiological or endotoxin controls than conventional food grade.

Pharmaceutical Formulations and Processing

Qualified pharmaceutical-grade Sodium Succinate may be used as an excipient, buffer component or process reagent.

Suitability depends on:

• Dosage form

• Route of administration

• Pharmacopoeial requirements

• Elemental impurities

• Endotoxin and bioburden limits

• Manufacturing quality system

• Stability and compatibility studies

• Destination-market regulations

This product page does not establish suitability for injectable or sterile products.

Laboratory and Analytical Use

Reagent-grade Disodium Succinate Anhydrous may be used in:

• Buffer preparation

• Analytical methods

• Biochemical assays

• Synthesis

• Method development

• Standard or reference-solution preparation

• Educational and research laboratories

Use the applicable reagent specification rather than a food-grade specification for analytical work.

Disodium Succinate and Other Flavor Enhancers

Disodium Succinate is not the same as monosodium glutamate, disodium inosinate or disodium guanylate.

Blends can produce effects that differ from those of each ingredient alone. Their use must comply with local regulations and finished-product labeling requirements.

Regulatory Considerations for Food Use

Disodium Succinate is identified by the U.S. FDA food-substance database as a flavor enhancer and flavoring agent or adjuvant under CAS No. 150-90-3 and FEMA No. 3277.

Codex-related nomenclature identifies Disodium Succinate as INS 364(ii), associated with acidity-regulating and flavor-enhancing functions.

However, authorization is not identical in every country. The European Union, United States, China, Japan and other markets may classify or regulate the ingredient through different food-additive or flavoring frameworks.

Before commercial use, confirm:

• Permitted product categories

• Maximum use level or GMP status

• Flavoring versus additive classification

• Required labeling name

• Purity criteria

• Source and natural-status requirements

• Import and registration requirements

A FEMA, INS or CAS number alone is not proof of authorization in every destination market.

Solubility and Processing Considerations

Disodium Succinate Anhydrous is soluble in water, but dissolution rate depends on particle size, temperature, concentration, agitation and the presence of other dissolved solids.

For reliable processing:

• Add the powder under controlled agitation.

• Avoid local overconcentration.

• Confirm final solution clarity.

• Check pH after complete dissolution.

• Evaluate compatibility with calcium and other multivalent ions.

• Protect dry powder from humidity before use.

• Confirm dissolution behavior at the intended production concentration.

Concentrated laboratory solubility data should not be treated as a finished-formulation guarantee.

Packaging and Storage

Depending on grade and quantity, packaging may include:

• Moisture-resistant bags

• Polyethylene-lined bags

• Fiber drums

• Plastic drums

• Food-compatible inner liners

• Small laboratory containers

• Palletized export packaging

Actual pack sizes and minimum order quantities must be confirmed in the quotation.

Store Disodium Succinate Anhydrous:

• In tightly closed packaging

• In a cool, dry and ventilated area

• Protected from moisture and contamination

• Away from strong acids and incompatible materials

• With food or pharmaceutical grade segregated from technical chemicals

• Within the temperature range stated by the supplier

Because the product is water soluble and the anhydrous form can absorb moisture, damaged or open packaging may affect flowability and assay.

Safety and Handling

Disodium Succinate Anhydrous is generally handled as a stable solid, but powder can cause mechanical irritation to the eyes or respiratory tract.

Recommended controls may include:

• Dust-minimizing transfer

• Local ventilation where needed

• Safety glasses

• Suitable gloves

• Protective work clothing

• Prompt cleanup of spills

• Good industrial hygiene

Confirm transport status, occupational controls and disposal requirements from the current Safety Data Sheet.

Documentation for Supplier Qualification

Depending on grade and market, buyers may request:

• Certificate of Analysis

• Safety Data Sheet

• Technical Data Sheet

• Product specification

• FEMA declaration

• Food-grade declaration

• Natural-origin statement where applicable

• Country-of-origin statement

• Allergen statement

• GMO statement

• Kosher certificate

• Halal certificate

• Microbiological data

• Bacterial endotoxin data

• Elemental-impurity statement

• USP/NF or other compendial statement

• Manufacturing-flow summary

• Change-notification policy

• Packaging specification

Document availability should be confirmed before the order is placed.

What to Include in a Disodium Succinate RFQ

For an accurate quotation, provide:

1. Anhydrous or hexahydrate form

2. CAS number

3. Required grade

4. Minimum assay

5. Maximum loss on drying

6. Chloride and sulfate limits

7. Lead, arsenic and elemental-impurity limits

8. Required particle size

9. Microbiological or endotoxin limits

10. Food, FEMA, NF or other compliance requirements

11. Packaging size

12. Order quantity and annual demand

13. Delivery country, city or port

14. Intended application

15. Required certificates and declarations

Frequently Asked Questions

What is Disodium Succinate Anhydrous?

Disodium Succinate Anhydrous is the water-free disodium salt of succinic acid. It has the formula C₄H₄Na₂O₄, molecular weight 162.05 g/mol and CAS number 150-90-3.

Is Disodium Succinate Anhydrous organic or inorganic?

It is an organic acid salt. Although it contains sodium ions, the succinate component is derived from the organic dicarboxylic acid known as succinic acid.

Is it a fine chemical or a chemical intermediate?

It is primarily a fine chemical and functional ingredient. It is used directly as a flavor ingredient, buffer component, reagent or specialty process material.

What is the difference between anhydrous and hexahydrate Disodium Succinate?

The anhydrous form contains no water of crystallization and has a molecular weight of 162.05 g/mol. The hexahydrate contains six water molecules and has a molecular weight of approximately 270.14 g/mol.

Can the anhydrous and hexahydrate forms be substituted one-to-one?

No. Their active succinate contents per kilogram differ. Dosage must be recalculated using molecular weight, assay and actual moisture.

Is Disodium Succinate the same as Succinic Acid?

No. Succinic Acid is the free dicarboxylic acid, while Disodium Succinate is its fully neutralized disodium salt. Their pH and taste profiles differ.

Is Disodium Succinate the same as MSG?

No. MSG is monosodium glutamate. Disodium Succinate is the disodium salt of succinic acid. Both can contribute savory character but have different chemical identities and flavor profiles.

What does FEMA 3277 mean?

FEMA 3277 is the identification number associated with Disodium Succinate in the Flavor and Extract Manufacturers Association system. It does not automatically establish authorization for every food category or country.

Is Disodium Succinate permitted in food worldwide?

Not automatically. Regulatory classification and permitted uses vary by jurisdiction. Confirm the applicable requirements for each destination market and food category.

Why use the anhydrous form in seasoning powders?

The anhydrous form provides more active succinate per kilogram and introduces no water of crystallization, which can be beneficial in dry, moisture-sensitive blends.

Is Disodium Succinate suitable for buffer preparation?

Yes, it can be used in succinate buffer systems. The final pH depends on the ratio of succinic acid to succinate, concentration, temperature and other solution components.

Which grade is suitable for bioprocess use?

A low-endotoxin or appropriately qualified pharmaceutical/bioprocess grade may be required. The actual endotoxin, trace-metal and microbiological limits should be stated in the purchase specification.

Request a Disodium Succinate Anhydrous Quote

Send us your required grade, assay, moisture limit, particle size, packaging, order quantity and delivery destination. We will confirm the applicable specification, available documentation and commercial terms.

For food applications, include the destination country and finished-food category. For pharmaceutical or bioprocess applications, provide the required compendial, microbiological and endotoxin limits.