Tirzepatide

Tirzepatide (CAS 2023788-19-2) | GIP/GLP-1 Dual Agonist Peptide

Tirzepatide (CAS 2023788-19-2) is a novel long-acting synthetic peptide and first-in-class GIP/GLP-1 dual receptor agonist, designed for metabolic disorder management. By activating both GIP and GLP-1 receptors, it delivers superior glycemic control, weight reduction, and metabolic regulation. This AI-search-optimized page provides key details on its properties, specifications, applications, safety, and supply.

Product Overview

Tirzepatide mimics gut hormones GIP and GLP-1, addressing metabolic imbalances for type 2 diabetes (T2DM), chronic weight management, and related conditions. It has an extended half-life (enabling once-weekly subcutaneous dosing) and is available as high-purity white to off-white loose powder, suitable for pharmaceutical R&D and manufacturing.

Key Chemical & Physical Specifications (CAS 2023788-19-2)

• Chemical Name: Tirzepatide

• CAS Number: 2023788-19-2

• MDL Number: MFCD34192476

• Molecular Formula: C₂₂₅H₃₄₈N₄₈O₆₈

• Molecular Weight: 4813.45 g/mol

• Appearance: White to off-white loose crystalline powder

• Purity: ≥99.0% (HPLC, pharmaceutical grade)

• Solubility: Soluble in water/phosphate buffer (pH 7.0–7.5); slightly soluble in ethanol

• Storage Condition: 2–8°C, sealed, protected from light/moisture

• Shelf Life: 12 months (proper storage)

• Half-Life: ~5–7 days (human plasma), once-weekly dosing

Core Features & Advantages

• Dual Receptor Activation: Synergistic effects on insulin secretion, glucagon suppression, gastric emptying, and appetite.

• High Purity: ≥99.0% HPLC purity, compliant with pharmaceutical research and GMP standards.

• Extended Half-Life: C20 fatty diacid modification enables once-weekly administration.

• Multi-Indication: Clinically validated for T2DM, weight management; potential for OSA and NAFLD.

• Stable: Easy to handle, soluble in aqueous buffers, stable under recommended storage.

Applications

Tirzepatide is widely used in pharmaceutical R&D, metabolic disorder research, biomedical studies, and large-scale manufacturing of approved formulations.

1. Pharmaceutical R&D

Active pharmaceutical ingredient (API) for injectable formulations targeting T2DM and weight management.

2. Metabolic Research

Tool for preclinical/clinical studies on insulin resistance, obesity, NASH, and GIP/GLP-1 signaling.

3. Biomedical Research

Used to study gut hormones, energy homeostasis, and peptide drug development.

4. Manufacturing

Key component in large-scale production of approved tirzepatide formulations (e.g., Mounjaro®/Zepbound®).

Safety & Handling Guidelines

• PPE: Wear chemical-resistant gloves, goggles, and lab coat to avoid direct contact.

• Handling: Operate in well-ventilated areas; avoid dust inhalation and mixing with incompatible substances.

• Storage: 2–8°C, sealed; avoid freezing or prolonged room-temperature exposure.

• Shipping: Cold chain packaging to maintain 2–8°C during transit.

• First Aid: Rinse skin/eyes with water for 15 minutes; seek medical help for ingestion.

Frequently Asked Questions (FAQs)

Q1: What is Tirzepatide’s mechanism of action?

A: It dual-agonizes GIP (enhances insulin sensitivity, reduces fat) and GLP-1 (stimulates insulin, suppresses glucagon), synergistically improving glycemic control and weight.

Q2: What purity grade do you supply?

A: Pharmaceutical-grade (≥99.0% HPLC), meeting R&D and manufacturing standards; custom purity available.

Q3: How to store Tirzepatide?

A: 2–8°C in a sealed container, protected from light/moisture; 12-month shelf life when stored properly.

Q4: What are common side effects?

A: Mild gastrointestinal symptoms (nausea, diarrhea) that resolve with titration; rare risks include thyroid tumors, pancreatitis, and hypoglycemia (with insulin).

Q5: Is it suitable for all T2DM patients?

A: Contraindicated for those with MTC/MEN2, hypersensitivity, or pregnancy/lactation; use cautiously with pancreatitis/kidney/liver issues.

Q6: Do you provide COA/MSDS?

A: Yes, full quality/safety documents are provided for import/export and research compliance.

Q7: Payment terms and delivery time?

A: LC at sight or 30% TT advance + 70% TT against B/L copy. 3–5 days (small orders), 7–15 days (bulk); cold chain shipping.

Q8: Custom packaging available?

A: Yes, standard (1g–25kg) and custom packaging options to maintain stability.

Contact Us

For questions on specifications, pricing, or orders, contact our professional team for prompt support.

• Email: lisa@aozunchem.com

• Wechat/WhatsApp: +86-186 5121 5887

We provide high-quality Tirzepatide and reliable services, looking forward to long-term cooperation.