Menadione (2-Methyl-1,4-naphthoquinone)

Product Overview

Menadione, commonly called vitamin K3, is a methyl-substituted naphthoquinone. Its quinone group participates in redox reactions, making it useful in derivative synthesis and laboratory studies of oxidative stress.

This product page covers menadione, CAS 58-27-5. It does not describe menadione sodium bisulfite (MSB) or menadione nicotinamide bisulfite (MNB).

Product Information

Please specify your required assay and test method when making an inquiry. Grade suitability should be evaluated from the complete specification, not the product name alone.

Chemical Structure and Properties

Menadione is the 2-methyl derivative of 1,4-naphthoquinone. It is light sensitive and has low water solubility. Solvent selection and protection from light should therefore be considered during formulation and processing.

Applications of Menadione

Animal Nutrition Intermediates

• Vitamin K3 derivative production: Used as a starting material for compounds such as MSB and MNB.

• Feed ingredient selection: Buyers developing premixes should specify the required derivative, menadione-equivalent content and applicable feed standard.

The parent compound and its feed-additive derivatives differ in composition and formulation behavior. They should not be treated as interchangeable materials.

Pharmaceutical Intermediates

• Vitamin K-related synthesis: Used in preparing selected derivatives and related chemical intermediates.

• Process development: Evaluated for reaction routes requiring a methyl-substituted quinone building block.

These applications require qualification for the intended manufacturing process and do not establish suitability as a finished medicine.

Chemical Synthesis and Biochemical Research

• Quinone chemistry: Used in studies of redox behavior and chemical transformations.

• Oxidative-stress research: Used as a laboratory reagent in cell-based studies.

Experimental biological activity should not be presented as evidence of an approved treatment.

Supply and Packaging

Packaging options include 25 kg fiber drums and 25 kg bags. Confirm the available pack type, protective inner packaging and order quantity before purchase.

Aozun can discuss specification requirements, export documentation and logistics arrangements for your destination.

Storage and Handling

• Store tightly closed in a cool, dry place, protected from light and heat.

• Avoid generating or breathing dust; use suitable ventilation, protective gloves and eye protection.

• Prevent ingestion and contact with skin and eyes. Menadione can cause irritation and allergic skin reactions.

• Prevent release into drains and surface water.

• Follow the supplied SDS for incompatible materials, disposal and any specific storage requirements.

Frequently Asked Questions

Is menadione the same product as MSB or MNB?

No. MSB and MNB are distinct menadione derivatives with different compositions and menadione-equivalent contents. Confirm the chemical identity and specification before comparing quotations.

Is this product suitable for human vitamin supplements?

It should not be selected for that purpose based on the name “vitamin K3.” Menadione differs from the K1 and K2 forms commonly used in human supplements.

What information is needed for a quotation?

Please provide the required assay and test method, intended application, quantity, packaging preference and delivery destination. Supporting documentation and sample availability can then be discussed.

Contact Us

For menadione specifications, product documentation or a quotation, contact Aozun with your requirements.

Email: lisa@aozunchem.com
WeChat / WhatsApp: +86-186-5121-5887