Sodium Monofluorophosphate

Sodium Monofluorophosphate (SMFP), chemically known as disodium monofluorophosphate, is a highly effective inorganic fluorophosphate compound renowned for its role in oral health and industrial applications.

Brand:
aozun
Synonym:
Sodium Monofluorophosphate
Appearance:
White crystal or powder
CAS No.:
10163-15-2
Molecular Formula:
Na2PO3F
Molecular Weight:
143
EINECS:
233-433-0

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Product Description

Product Description

Key Features and Benefits

Superior Fluoride Delivery: Releases fluoride ions slowly for prolonged protection against demineralization and enamel erosion.
Mild and Biocompatible: Less abrasive than other fluorides, reducing the risk of enamel wear while maintaining oral tissue safety.
High Solubility: Dissolves completely in aqueous systems (>42 g/100 mL at 25°C), ensuring uniform distribution in gels, pastes, and rinses.
pH Stability: Aqueous solutions maintain a neutral to slightly alkaline pH (6.5-8.0), ideal for sensitive formulations.
Versatile Compatibility: Integrates seamlessly with humectants, abrasives, and surfactants without compromising product stability or sensory attributes.
Regulatory Compliance: Meets pharmacopeial standards for oral care ingredients, supporting claims for anti-caries efficacy.

Applications

SMFP is a cornerstone ingredient in preventive oral care and select industrial processes, delivering reliable performance across diverse uses:

Toothpastes and Dentifrices: Acts as the primary anti-caries agent in fluoride toothpastes, achieving up to 24% reduction in cavity formation per clinical studies.
Mouthwashes and Rinses: Enhances fluoride uptake in over-the-counter and professional dental rinses for daily or therapeutic use.
Professional Dental Treatments: Used in varnishes, gels, and prophy pastes for in-office applications targeting high-risk patients.
Food Supplements: Incorporated into chewable tablets and lozenges as a dietary fluoride source for children and adults.
Industrial Uses: Serves as a metal surface cleaner, flux in soldering, and additive in special glass manufacturing to improve durability and corrosion resistance.
Water Fluoridation: Applied in municipal systems at low concentrations (0.1-500 mg/L) to inhibit lead dissolution and promote public dental health.

Incorporating SMFP enables products to align with ADA and WHO guidelines for fluoride delivery, ensuring optimal protection without excessive intake risks.

Product Specifications

Property	Specification
CAS Number	10163-15-2
EC Number	233-433-0
Molecular Formula	Na₂PO₃F
Molecular Weight	143.95 g/mol
Appearance	White crystalline powder
Purity (HPLC)	≥98.0%
Melting Point	625°C (decomposition)
Solubility in Water	>42 g/100 mL at 25°C
pH (2% Aqueous Solution)	6.5-8.0
Loss on Drying	≤1.0%
Fluoride Content	19.0-21.0% (as F)
Packaging	25 kg fiber drums or 1 kg bags
Shelf Life	36 months in sealed containers

Note: Specifications are based on USP/EP pharmacopeial grades. Custom purities and particle sizes available for specific needs. Each lot is tested for heavy metals (≤10 ppm) and microbial limits.

Safety and Handling Information

SMFP is generally recognized as safe (GRAS) for oral care use at concentrations up to 1.5% fluoride equivalent, but requires careful handling in bulk form to avoid irritation. Essential precautions include:

Personal Protective Equipment (PPE): Use gloves, safety goggles, and dust masks during transfer to prevent skin, eye, or respiratory exposure.
Storage: Store in a cool, dry, well-ventilated area below 30°C, away from acids and moisture to prevent hydrolysis.
First Aid: For ingestion, do not induce vomiting; seek immediate medical advice. Rinse skin/eyes with water for 15 minutes and consult a physician if irritation persists.
Spill Response: Sweep up dry material or absorb with inert media; avoid generating dust. Dispose as non-hazardous waste per local regulations.
Environmental: Low ecotoxicity; biodegradable in aqueous environments. Fluoride levels in effluents should be monitored to comply with discharge limits.

Refer to the Safety Data Sheet (SDS) for comprehensive hazard classifications (H302, H315, H319) and exposure controls.

Frequently Asked Questions (FAQs)

What is Sodium Monofluorophosphate (SMFP)?

SMFP (CAS 10163-15-2) is a water-soluble inorganic salt used as a fluoride source in dental products. Its formula Na₂PO₃F enables controlled release of fluoride to strengthen tooth enamel and prevent decay.

What are the primary applications of SMFP?

SMFP is mainly used in toothpastes, mouthwashes, and dental treatments for anti-caries protection. It also finds roles in food supplements, water treatment, metal cleaning, and glass production.

Is SMFP safe for use in oral care products?

Yes, at recommended levels (up to 1,000-1,500 ppm fluoride), SMFP is safe and effective, with a milder profile than sodium fluoride. It is approved by regulatory bodies like the FDA and ADA for consumer use.

How does SMFP compare to sodium fluoride?

SMFP offers slower fluoride release for deeper enamel penetration and less aftertaste, making it suitable for sensitive users. Both provide similar cavity prevention, but SMFP is less reactive with formulation components.

What is the solubility and pH of SMFP?

SMFP is highly soluble in water (>42% at 25°C) and forms a neutral to slightly alkaline solution (pH 6.5-8.0 at 2%), ensuring compatibility with most oral care bases.

Can SMFP be used in custom formulations?

Yes, our high-purity SMFP is adaptable for bespoke products, including low-fluoride variants for children or high-concentration professional gels. Technical support is available for optimization.