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4-Chloropropiophenone

4-Chloropropiophenone is mainly used as a pharmaceutical intermediate, especially as a key intermediate in the synthesis of new weight loss drugs such as rimonabant. It can also be used as a fine chemical raw material for the synthesis of compounds containing para chlorobenzene ring structure, and can be used as an intermediate for other pharmaceuticals, pesticides, etc
  • White crystals

  • 6285-05-8

  • C9H9ClO

  • 168.62

Availability:

Product Description

4-Chloropropiophenone


Product Overview


4-Chloropropiophenone is an aromatic ketone widely used as a chemical intermediate in pharmaceutical, agrochemical, and fine chemical synthesis. It features a para-chloro–substituted phenyl ring combined with a propiophenone structure, providing predictable reactivity in carbonyl-related transformations.

Due to its stable structure and consistent performance, 4-chloropropiophenone is commonly applied in research laboratories and industrial manufacturing processes that require reliable aromatic ketone intermediates.




Key Product Identification


  • Product Name: 4-Chloropropiophenone

  • Synonyms: p-Chloropropiophenone, 1-(4-Chlorophenyl)propan-1-one

  • Chemical Formula: C₉H₉ClO

  • CAS Number: 6285-05-8

  • Molecular Weight: 168.62 g/mol

  • HS Code: 29143900

  • Appearance: Colorless to pale yellow liquid or crystalline solid

  • Odor: Mild aromatic odor




Chemical & Physical Properties

Property Typical Value
Purity ≥ 98.0%
Physical State Liquid or solid (depending on temperature)
Boiling Point ~ 256 °C
Solubility Soluble in most organic solvents
Functional Group Aromatic ketone

Values shown are typical for industrial and export-grade material.




Manufacturing & Quality Control


4-Chloropropiophenone is produced through controlled Friedel–Crafts acylation or related aromatic acylation processes. Strict process control ensures consistent purity and batch stability.

Quality control procedures include:


  • Purity testing (GC / HPLC)

  • Moisture and impurity analysis

  • Appearance and color inspection

  • Batch traceability documentation


Each shipment is supplied with complete quality documentation.




Applications of 4-Chloropropiophenone


Pharmaceutical Intermediates

Used as a building block in the synthesis of pharmaceutical intermediates and active compound precursors.


Agrochemical Intermediates

Applied in the production of herbicide and pesticide intermediates requiring aromatic ketone structures.


Fine Chemicals & Custom Synthesis

Used in specialty chemical manufacturing, contract synthesis, and laboratory-scale research.


Chemical Research

Commonly used in organic synthesis involving carbonyl modification, reduction, or condensation reactions.




Packaging & Logistics


  • Standard Packaging:

    • 25 kg fiber drum

    • 25 kg plastic drum

  • Custom Packaging: Available upon request

  • Storage Conditions:

    • Store in a cool, dry, and well-ventilated area

    • Keep containers tightly closed and protected from heat




Safety & Handling


  • Avoid contact with skin and eyes

  • Use appropriate personal protective equipment (PPE)

  • Handle in accordance with standard industrial safety practices

  • Refer to the Safety Data Sheet (SDS/MSDS) before use




Regulatory & Documentation


Available upon request:

  • COA (Certificate of Analysis)

  • SDS / MSDS

  • TDS (Technical Data Sheet)

  • Export and regulatory compliance documents




Why Choose Our 4-Chloropropiophenone?


  • ✔ Consistent purity and stable batch quality

  • ✔ Suitable for pharmaceutical and fine chemical synthesis

  • ✔ Export-ready packaging and documentation

  • ✔ Flexible MOQ and logistics support

  • ✔ Professional technical service




Frequently Asked Questions (FAQ)


Q1: Is 4-Chloropropiophenone suitable for pharmaceutical synthesis?


Yes, it is widely used as a pharmaceutical and chemical intermediate.


Q2: Is this product supplied as a liquid or solid?


It may appear as a liquid or crystalline solid depending on ambient temperature.


Q3: Do you provide analytical documents?


Yes, COA and SDS are supplied with each batch.


Q4: What is the typical minimum order quantity (MOQ)?


MOQ depends on packaging type and destination; please contact us for details.


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