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4-Bromobenzenesulfonyl Chloride

4-Bromobenzenesulfonyl chloride, as an important organic intermediate, has been increasingly widely used in the synthesis of angiotensin II AT1/AT2 receptor antagonists, as well as in the synthesis of endothelin receptor antagonists. In addition to being used for synthesizing biologically active insecticides, 4-bromobenzenesulfonyl chloride is increasingly demonstrating its potential application value in the field of new drug research.
  • White powder

  • 98-58-8

  • C6H4BrClO2S

  • 255.52

  • 202-683-2

Availability:

Product Description

4-Bromobenzenesulfonyl Chloride


Product Overview


4-Bromobenzenesulfonyl Chloride is an aromatic sulfonyl chloride widely used as a key intermediate in pharmaceutical, agrochemical, and fine chemical synthesis. Due to its highly reactive sulfonyl chloride functional group, it is commonly employed in sulfonylation reactions for the preparation of sulfonamides, sulfonate esters, and functionalized aromatic compounds.

This compound is valued for its consistent reactivity and reliability in both industrial-scale manufacturing and laboratory research.




Key Product Identification


  • Product Name: 4-Bromobenzenesulfonyl Chloride

  • Synonyms: p-Bromobenzenesulfonyl Chloride

  • Chemical Formula: C₆H₄BrClO₂S

  • CAS Number: 98-65-7

  • Molecular Weight: 271.52 g/mol

  • HS Code: 29041000

  • Appearance: White to pale yellow crystalline solid

  • Odor: Pungent, characteristic sulfonyl chloride odor




Chemical & Physical Properties


Property Typical Value
Purity ≥ 98.0%
Physical State Solid
Reactivity Reacts readily with amines and alcohols
Solubility Soluble in most organic solvents
Moisture Sensitivity Moisture-sensitive

Typical values for industrial and export-grade material.




Manufacturing & Quality Control


4-Bromobenzenesulfonyl Chloride is produced via controlled sulfonation and chlorination of bromobenzene derivatives under strictly monitored conditions. Each production batch is subjected to comprehensive quality control, including:


  • Purity analysis (HPLC / GC)

  • Moisture and impurity control

  • Appearance and color inspection

  • Batch traceability and consistency testing

All shipments are supplied with complete quality documentation.




Applications of 4-Bromobenzenesulfonyl Chloride


Pharmaceutical Intermediates

Used in the synthesis of sulfonamide-based drug intermediates and API building blocks.


Agrochemical Synthesis

Applied in the manufacture of herbicide and pesticide intermediates requiring aromatic sulfonyl functionality.


Fine Chemicals & Specialty Synthesis

Used in specialty chemical production, custom synthesis, and contract manufacturing.


Research & Development

Common reagent in organic chemistry laboratories for sulfonylation reactions.




Packaging & Logistics


  • Standard Packaging:

    • 25 kg fiber drum

    • 25 kg plastic drum

  • Custom Packaging: Available upon request

  • Storage Conditions:

    • Store in a cool, dry, well-ventilated area

    • Keep containers tightly sealed and protected from moisture




Safety & Handling


  • Corrosive and moisture-reactive chemical

  • Avoid contact with skin, eyes, and inhalation

  • Use appropriate personal protective equipment (PPE)

  • Handle under dry and well-ventilated conditions

  • Refer to the Safety Data Sheet (SDS/MSDS) before use




Regulatory & Documentation


Available upon request:

  • COA (Certificate of Analysis)

  • SDS / MSDS

  • TDS (Technical Data Sheet)

  • Export and regulatory compliance documents




Why Choose Our 4-Bromobenzenesulfonyl Chloride?


  • ✔ Stable purity and batch consistency

  • ✔ Suitable for pharmaceutical and agrochemical synthesis

  • ✔ Export-ready packaging and documentation

  • ✔ Flexible MOQ and logistics options

  • ✔ Professional technical support




Frequently Asked Questions (FAQ)


Q1: Is 4-Bromobenzenesulfonyl Chloride moisture sensitive?


Yes, it reacts with moisture and should be stored and handled under dry conditions.


Q2: What are the main applications of this product?


It is mainly used in pharmaceutical, agrochemical, and fine chemical synthesis.


Q3: Can you provide analytical and regulatory documents?


Yes, COA, SDS, and additional documents are available for each batch.


Q4: What is the typical minimum order quantity (MOQ)?


MOQ depends on packaging and destination; please contact us for specific details.


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