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4-Aminopyridine

4-Aminopyridine precipitated from benzene is a colorless needle shaped crystal with an ammonia odor, which can be used as an intermediate in pesticides, pharmaceuticals, and dyes; Also used as a chemical reagent.
  • 504-24-5

  • C5H6N2

  • 94.11

  • 207-987-9

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Product Description

4-Aminopyridine


Product Overview


4-Aminopyridine (C₅H₆N₂) is a colorless to light yellow crystalline organic compound widely used as a pharmaceutical intermediate, neurophysiological research reagent, and specialty chemical building block. Known for its amino group attached to the pyridine ring, it serves as a versatile compound in medicinal chemistry, organic synthesis, and chemical research.


4-Aminopyridine is valued for its high purity, stability, and reactivity, making it an essential reagent for drug development and laboratory applications.




Key Product Identification


  • Product Name: 4-Aminopyridine

  • Synonyms: 4-Pyridinamine, p-Aminopyridine

  • Chemical Formula: C₅H₆N₂

  • CAS Number: 504-24-5

  • Molecular Weight: 94.11 g/mol

  • HS Code: 29214200

  • Appearance: Colorless to light yellow crystalline solid

  • Odor: Slight amine odor

  • Solubility: Soluble in water, ethanol, and other polar organic solvents




Chemical & Physical Properties


Property Typical Value
Purity ≥ 99%
Melting Point 200 – 205 °C (decomposes)
Density 1.13 g/cm³
Stability Stable under dry and cool conditions; avoid strong oxidizing agents
Reactivity Amino group reacts in diazotization, acylation, and substitution reactions
Storage Store in a cool, dry, well-ventilated area; protect from light



Manufacturing & Quality Control


4-Aminopyridine is synthesized via reduction of 4-nitropyridine or amination reactions under controlled conditions. Quality control ensures:


  • High chemical purity and minimal residual solvents

  • Consistent crystallinity and particle size

  • Compliance with laboratory and pharmaceutical intermediate standards


Each batch undergoes HPLC/GC assay, melting point verification, and visual inspection to ensure reliability.




Applications of 4-Aminopyridine


Pharmaceutical & Medicinal Chemistry

  • Intermediate for neuroactive drugs and pharmaceutical compounds

  • Used in research for potassium channel blockers and neurological disorder studies


Organic Synthesis & Research

  • Key building block for heterocyclic compounds, dyes, and specialty chemicals

  • Applied in laboratory research and chemical method development


Neurophysiological Research

  • Serves as a potassium channel blocker in electrophysiology studies

  • Used to study nerve signal conduction and synaptic transmission



Packaging & Logistics


  • Standard Packaging:

    • 25 g, 100 g, 500 g, 1 kg powder in sealed amber glass or HDPE containers


  • Bulk Supply: Available upon request


  • Storage Conditions:

    • Store in cool, dry, and well-ventilated conditions

    • Protect from moisture, heat, and strong oxidizing agents

    • Keep containers tightly sealed




Safety & Handling


  • Avoid inhalation, ingestion, and prolonged skin contact; use standard laboratory PPE

  • Handle under fume hood or well-ventilated area

  • Consult the Safety Data Sheet (SDS/MSDS) for detailed handling, storage, and emergency instructions




Regulatory & Documentation


Available upon request:

  • COA (Certificate of Analysis)

  • SDS / MSDS

  • TDS (Technical Data Sheet)

  • Compliance with laboratory and pharmaceutical intermediate standards




Why Choose Our 4-Aminopyridine?


  • ✔ High purity and reliable batch-to-batch consistency

  • ✔ Suitable for pharmaceutical intermediates, research, and chemical synthesis

  • ✔ Flexible packaging and bulk supply options

  • ✔ Export-ready documentation and regulatory support

  • ✔ Technical guidance for laboratory and industrial applications




Frequently Asked Questions (FAQ)


Q1: What is 4-Aminopyridine used for?


It is used as a pharmaceutical intermediate, neurophysiological research reagent, and building block in organic synthesis.


Q2: Is 4-Aminopyridine soluble in water?


Yes, it is soluble in water and polar organic solvents such as ethanol and methanol.


Q3: Can you provide analytical and regulatory documents?


Yes, COA, SDS, TDS, and compliance certificates are available.


Q4: What is the typical minimum order quantity (MOQ)?


MOQ depends on packaging type and destination; please contact us for details.


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