Triphenylphosphine Oxide (TPPO) CAS 791-28-6

What Is Triphenylphosphine Oxide?

Triphenylphosphine oxide, commonly abbreviated as TPPO, is an organophosphorus compound with the molecular formula C18H15OP and CAS No. 791-28-6. It normally appears as a white to off-white crystalline powder or flakes.

TPPO is used in organic synthesis, coordination chemistry, crystallization research, analytical testing and specialty chemical development. It is also commonly encountered as an oxidation product of triphenylphosphine.

Triphenylphosphine Oxide Identification and Properties

The appearance, assay and melting range shown above are typical reference information. Final acceptance requirements should be confirmed against the agreed specification and batch Certificate of Analysis.

Is TPPO Organic or Inorganic?

Triphenylphosphine oxide is an organic compound. It contains three phenyl groups directly bonded to phosphorus and is classified more specifically as an organophosphorus compound.

For commercial website categorization, TPPO is best placed under Fine Chemicals. Depending on its intended use, it may also be described as an organophosphorus intermediate, synthetic reagent or laboratory chemical.

How Is TPPO Different from Triphenylphosphine and Triphenyl Phosphate?

These products have similar names but are different chemicals.

Buyers should always confirm the complete chemical name, CAS number and molecular formula before placing an order.

What Is Triphenylphosphine Oxide Used For?

Organic Synthesis

TPPO is used as a reagent, intermediate or process-related material in organophosphorus chemistry and specialty organic synthesis. It may also be monitored as a reaction-related impurity when triphenylphosphine is used.

Coordination Chemistry

The phosphoryl oxygen in TPPO can coordinate with metal ions. This makes the product useful in ligand studies, metal-complex research and separation chemistry.

Crystallization Research

TPPO can participate in molecular association and crystallization processes. It is used in crystallization studies, solid-state chemistry and the development of specialty crystalline materials.

Analytical and Impurity Testing

TPPO standards can be used to identify or quantify triphenylphosphine oxide in reaction mixtures and finished products using HPLC, GC, NMR or other suitable analytical methods.

Materials and Catalyst Research

TPPO is also evaluated in catalyst systems, functional materials, nanomaterial research and other application-development projects.

Which TPPO Grade Do You Need?

The suitable grade depends on how the product will be used.

Customers should provide the intended application and required test method when requesting a quotation.

Which TPPO Quality Attributes Should Buyers Compare?

Purity alone is not enough; identity, residual triphenylphosphine, melting range and application-specific impurities should be evaluated together.

Before approving a commercial batch, buyers should confirm the analytical method and acceptance limit for each critical parameter.

Packaging, Storage and Handling

Triphenylphosphine oxide should be supplied in clean, tightly sealed and chemically compatible packaging. Available pack size and packaging configuration should be confirmed during quotation.

Store the product in a cool, dry and well-ventilated place, away from incompatible materials and contamination. Keep the container closed when not in use.

Operators should follow the current Safety Data Sheet and use suitable gloves, eye protection and workplace controls. Avoid generating or inhaling dust and prevent release to the environment.

Which Documents Should a TPPO Supplier Provide?

Depending on the application and order requirements, buyers may request:

• Batch Certificate of Analysis

• Safety Data Sheet

• Product specification

• Analytical method or chromatographic information

• Country-of-origin statement

• Packaging information

• Retest date or shelf-life information

• Additional impurity or metal testing where required

Document requirements should be confirmed before the order is finalized.

Why Source Triphenylphosphine Oxide from AOZUN?

AOZUN can assist customers with TPPO grade selection, specification matching, sample evaluation and commercial order coordination.

To receive an accurate quotation, please provide:

• Required purity and analytical method

• Intended application

• Critical impurity limits

• Required quantity

• Packaging requirements

• Destination country

• Required technical or regulatory documents

Final specifications, packaging, availability and supporting documents are confirmed according to the selected product and commercial order.

Triphenylphosphine Oxide FAQ

Is Triphenylphosphine Oxide the Same as Triphenylphosphine?

No. Triphenylphosphine oxide has CAS No. 791-28-6, while triphenylphosphine has CAS No. 603-35-0. Triphenylphosphine can be oxidized to form triphenylphosphine oxide.

Is TPPO the Same as Triphenyl Phosphate?

No. Triphenyl phosphate is a phosphate ester with CAS No. 115-86-6 and molecular formula C18H15O4P. It is chemically different from triphenylphosphine oxide.

Why Does TPPO Appear in Organic Reaction Mixtures?

TPPO is frequently produced when triphenylphosphine is oxidized during a reaction. For this reason, it may need to be separated or monitored as a process-related impurity.

Should TPPO Purity Be Tested by GC or HPLC?

Both methods may be used, but their results are method-dependent. Buyers should specify the required method and review the chromatographic conditions before comparing products from different suppliers.

Is a High Assay Enough to Approve a TPPO Batch?

Not always. Residual triphenylphosphine, related substances, moisture, residual solvents and metal impurities may also affect downstream performance.

Request a TPPO Quotation

Contact AOZUN for Triphenylphosphine Oxide, CAS No. 791-28-6. Please include your target specification, application, quantity, packaging and delivery destination so that the appropriate product option can be evaluated.