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Tetrakis(hydroxymethyl)phosphonium Sulfate (THPS)

Tetrakis(hydroxymethyl)phosphonium sulfate (THPS) is a water-soluble, non-oxidizing organophosphorus biocide commonly supplied as a 75% aqueous solution. It is used for microbial control in oilfield operations, industrial water systems, and pulp and paper processes.
  • aozun

  • Tetrakis(Hydroxymethyl) Phosphonium Sulfate

  • Transparent liquid in appearance

  • 55566-30-8

  • [(HOCH2)4P]2 SO4

  • 406.28 g/mol

  • 259-709-0

  • soluble in water

Availability:

Product Description

Key Features and Benefits

  • Microbial Control: Used to control sulfate-reducing bacteria and other unwanted microorganisms in selected industrial systems.

  • Water Solubility: Can be incorporated into aqueous treatment programs, with compatibility evaluated for the specific process.

  • Support for MIC Control: Helps manage microorganisms associated with microbiologically influenced corrosion as part of a suitable treatment program.


Applications


THPS delivers robust microbial control in challenging environments, supporting operational efficiency and regulatory compliance:


  • Oil and Gas: Controls bacterial growth in drilling fluids, fracturing operations, produced water, and injection systems to prevent H₂S souring, reservoir plugging, and MIC in pipelines and tanks.


  • Industrial Water Treatment: Inhibits biofilm formation in cooling towers, boilers, and process water loops, enhancing heat transfer and reducing downtime in power plants, refineries, and manufacturing facilities.


  • Pulp and Paper: Prevents slime deposits on machinery and in whitewater systems, improving paper quality and machine runnability while meeting hygiene standards.


  • Wastewater Management: Targets anaerobic bacteria in digesters and effluents, aiding odor control and treatment efficacy in municipal and industrial plants.


Product Specifications


Property Specification
CAS Number 55566-30-8
EC Number 259-709-0
Molecular Formula C₈H₂₄O₁₂P₂S
Molecular Weight 406.28 g/mol
Appearance Clear, colorless to pale yellow liquid
Assay (THPS Content) 70.0-80.0% (w/w)
pH (10% Aqueous Solution) 3.5-5.5
Density 1.32-1.38 g/mL at 20°C
Viscosity <100 cP at 25°C
Solubility in Water Completely miscible
Active Phosphorus 8.5-9.5%
Packaging 200 L drums, 1,000 L IBCs, bulk tankers


Note: Technical and custom concentrations (50-75%) available. Each batch is analyzed for microbial efficacy and heavy metals (≤10 ppm total).


Safety and Handling Information

  • Review the current SDS for the supplied concentration before handling.

  • Avoid skin and eye contact and inhalation of mist. Use suitable protective equipment and ventilation as specified in the SDS.

  • Keep containers tightly closed and follow the stated storage conditions and compatibility requirements.

  • Follow the product SDS and site procedures for first aid, spills, disposal and transport. Prevent uncontrolled release to the environment.


Frequently Asked Questions (FAQs)


What is Tetrakis(Hydroxymethyl) Phosphonium Sulfate (THPS)?

THPS (CAS 55566-30-8) is a quaternary phosphonium biocide supplied as an aqueous solution. Its structure features four hydroxymethyl groups on a phosphorus center paired with sulfate, enabling potent antimicrobial action through cell membrane disruption.


What are the primary applications of THPS?

THPS is mainly used in oil and gas for souring prevention and corrosion control, industrial water systems for biofilm inhibition, and pulp/paper processes for slime control. It excels in environments prone to SRB and fungal growth.


Is THPS environmentally safe?

THPS can degrade under suitable conditions, but concentrated solutions still present health and aquatic hazards. Biodegradability does not mean the product is harmless or suitable for unrestricted discharge. Follow the supplied SDS and applicable treatment and discharge requirements.


What is the typical concentration and dosing for THPS?

THPS is commonly supplied as a 75% aqueous solution. The treatment dose depends on the application, microbial contamination, water chemistry and contact time. Confirm whether any stated dosage refers to active THPS or the supplied solution, and establish the treatment program through appropriate testing and product-label instructions.


What storage and handling precautions are needed for THPS?

Store in cool, sealed containers away from incompatibles. Handle with PPE to avoid skin/eye contact, and ensure proper ventilation. Shelf life is 24 months when protected from light and heat.


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