Sodium Triacetoxyborohydride

Product Overview

Sodium Triacetoxyborohydride (NaBH(OAc)₃) is a mild and selective reducing agent widely used in organic synthesis, reductive amination, and pharmaceutical intermediate production. It is valued for its stability in protic solvents, selective reduction of imines and aldehydes, and compatibility with sensitive functional groups.

Sodium Triacetoxyborohydride is ideal for laboratory and industrial applications where controlled and efficient reductions are required, making it a core reagent in fine chemical, pharmaceutical, and specialty organic synthesis.

Key Product Identification

• Product Name: Sodium Triacetoxyborohydride

• Synonyms: NaBH(OAc)₃, STAB, Sodium Triacetoxyborohydride

• Chemical Formula: C₆H₉BO₆Na

• CAS Number: 56553-60-7

• Molecular Weight: 221.94 g/mol

• HS Code: 28352100

• Appearance: White to off-white crystalline powder

• Odor: Odorless

• Solubility: Soluble in dichloromethane, acetonitrile, and other aprotic solvents; hydrolyzes in water

Chemical & Physical Properties

Values are typical for reagent-grade material.

Manufacturing & Quality Control

Sodium Triacetoxyborohydride is manufactured via controlled reaction of sodium borohydride with acetic acid or acetic anhydride under dry, inert conditions. Quality control ensures:

• High chemical purity and reproducibility

• Low residual moisture and by-products

• Compliance with laboratory and pharmaceutical intermediate standards

Each batch undergoes assay, moisture content, and purity verification to ensure reliability and performance.

Applications of Sodium Triacetoxyborohydride

Reductive Amination

• Efficiently reduces imines and aldehydes to amines under mild conditions

• Widely used in pharmaceutical and fine chemical synthesis

Organic Synthesis

• Enables selective reductions in multifunctional molecules

• Compatible with sensitive functional groups such as esters, ketones, and nitriles

Pharmaceutical Intermediates

• Key reagent for drug intermediates and active pharmaceutical ingredient (API) synthesis

• Facilitates high yield and stereoselective reactions

Laboratory & Research

• Applied in academic and industrial laboratories for method development and reaction optimization

• Preferred for stable, easy-to-handle reducing agent in aprotic solvents

Packaging & Logistics

• Standard Packaging:

• 25 g, 100 g, 500 g, 1 kg powder in sealed amber HDPE or glass bottles

• Bulk Supply: Available upon request with secure packaging

• Storage Conditions:

• Store in cool, dry, and inert conditions

• Protect from moisture and water

• Keep containers tightly sealed and away from heat sources

Safety & Handling

• Moisture-sensitive; reacts with water to release hydrogen gas

• Avoid skin and eye contact; use standard laboratory PPE

• Handle under dry, inert conditions for storage and reaction

• Consult the Safety Data Sheet (SDS/MSDS) for detailed handling and emergency procedures

Regulatory & Documentation

Available upon request:

• COA (Certificate of Analysis)

• SDS / MSDS

• TDS (Technical Data Sheet)

• Compliance with laboratory and pharmaceutical intermediate standards

Why Choose Our Sodium Triacetoxyborohydride?

• ✔ High reagent-grade purity and consistent batch quality

• ✔ Ideal for reductive amination, selective reductions, and pharmaceutical intermediate synthesis

• ✔ Flexible packaging and bulk supply options

• ✔ Export-ready documentation and regulatory support

• ✔ Technical guidance for laboratory and industrial applications

Frequently Asked Questions (FAQ)

Q1: What is Sodium Triacetoxyborohydride used for?

It is used as a mild reducing agent in reductive amination, selective reductions, and pharmaceutical intermediate synthesis.

Q2: Is it soluble in water?

It hydrolyzes in water and is not stable in aqueous solutions; it is soluble in aprotic organic solvents like dichloromethane and acetonitrile.

Q3: Can you provide analytical and regulatory documents?

Yes, COA, SDS, TDS, and compliance certificates are available.

Q4: What is the typical minimum order quantity (MOQ)?

MOQ depends on packaging type and destination; please contact us for details.