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N,N-Dimethylformamide

N,N-Dimethylformamide (DMF) is a colorless, hygroscopic liquid with the molecular formula C₃H₇NO. DMF is a polar aprotic solvent known for its excellent solvency, high boiling point, and chemical stability, making it widely used in organic synthesis, polymer production, pharmaceuticals, and chemical research.
  • 68-12-2

  • C3H7NO

  • 73.09

  • 200-679-5

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DESCRIPTION

N,N-Dimethylformamide (DMF)


Product Overview


N,N-Dimethylformamide (DMF) is a colorless, hygroscopic liquid with the molecular formula C₃H₇NO. DMF is a polar aprotic solvent known for its excellent solvency, high boiling point, and chemical stability, making it widely used in organic synthesis, polymer production, pharmaceuticals, and chemical research.

DMF is particularly valued for its ability to dissolve polar and non-polar compounds, facilitating reactions in peptide synthesis, polyurethane production, and fine chemical manufacturing.




Key Product Identification


  • Product Name: N,N-Dimethylformamide (DMF)

  • Synonyms: Dimethylformamide, DMF, N,N-DMF

  • Chemical Formula: C₃H₇NO

  • CAS Number: 68-12-2

  • Molecular Weight: 73.09 g/mol

  • HS Code: 29173900

  • Appearance: Colorless to slightly yellow liquid

  • Odor: Amine-like odor




Chemical & Physical Properties


Property Typical Value
Purity ≥ 99.5%
Boiling Point 153 °C
Melting Point −61 °C
Density (20 °C) 0.944 g/cm³
Solubility Miscible with water and most organic solvents
Flash Point 58 °C
Viscosity 0.92 cP (25 °C)

Values shown are typical for industrial and laboratory-grade DMF.




Manufacturing & Quality Control


DMF is primarily produced by catalytic oxidation of dimethylamine and carbon monoxide. Production is controlled to ensure:


  • High purity and low water content

  • Minimal levels of impurities and residual amines

  • Consistent physical and chemical properties

Each batch undergoes comprehensive quality testing, including purity, water content, and color, ensuring compliance with industrial and laboratory standards.




Applications of N,N-Dimethylformamide (DMF)


Pharmaceutical Industry

Used as a solvent and reaction medium in API synthesis, peptide synthesis, and fine chemical manufacturing.


Polymer & Resin Production

Key solvent in polyurethane, polyacrylonitrile, and PVC processing, providing excellent solubility and process control.


Chemical Research

Commonly used as a polar aprotic solvent for organic reactions, coupling reactions, and condensation reactions.


Coatings, Paints & Adhesives

Employed in coatings, inks, and adhesives for its high solvency and chemical stability.



Packaging & Logistics


  • Standard Packaging:

    • 200 L steel drum

    • 1000 L IBC tank

  • Bulk Supply: Available

  • Storage Conditions:

    • Store in a cool, dry, well-ventilated area

    • Keep containers tightly sealed and protected from ignition sources

    • Avoid exposure to moisture and strong oxidizers




Safety & Handling


  • Flammable liquid and moderate health hazard

  • Avoid inhalation, skin, and eye contact

  • Use appropriate personal protective equipment (PPE)

  • Handle in accordance with standard industrial safety procedures

  • Refer to the Safety Data Sheet (SDS/MSDS) before use




Regulatory & Documentation


Available upon request:

  • COA (Certificate of Analysis)

  • SDS / MSDS

  • TDS (Technical Data Sheet)

  • REACH and other regulatory compliance documents




Why Choose Our N,N-Dimethylformamide (DMF)?


  • ✔ Ultra-high purity suitable for industrial and laboratory applications

  • ✔ Stable and consistent batch quality

  • ✔ Flexible packaging and bulk supply options

  • ✔ Export-ready documentation and logistics support

  • ✔ Technical and regulatory support for customers




Frequently Asked Questions (FAQ)


Q1: Is DMF suitable for pharmaceutical synthesis?


Yes, DMF is widely used as a solvent in pharmaceutical and fine chemical synthesis.


Q2: Can DMF be used in polymer production?


Yes, DMF is commonly used in polyurethane, polyacrylonitrile, and PVC manufacturing.


Q3: Do you provide analytical and regulatory documents?


Yes, COA, SDS, TDS, and compliance documents are supplied with each batch.


Q4: What is the typical minimum order quantity (MOQ)?


MOQ depends on packaging type and destination; please contact us for details.


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