Methyl 2-Sulfanylacetate (Mercaptoacetic Acid Methyl Ester)
CAS Number: 2365-48-2
Methyl 2-sulfanylacetate, also known as Mercaptoacetic Acid Methyl Ester, is an important thiol-containing organic intermediate widely used in chemical synthesis, pharmaceuticals, agrochemicals, and specialty materials. Due to its reactive –SH (thiol) functional group, this compound serves as a versatile building block in the preparation of sulfur-containing molecules and fine chemicals.
This product is commonly supplied as a clear to slightly yellow liquid and is valued for its strong reactivity, stable quality, and broad industrial applications.
Key Product Information
| Property | Value |
|---|---|
| Product Name | Methyl 2-sulfanylacetate |
| Synonyms | Mercaptoacetic Acid Methyl Ester; Methyl Thioglycolate |
| CAS Number | 2365-48-2 |
| Molecular Formula | C₃H₆O₂S |
| Molecular Weight | 106.14 g/mol |
| Appearance | Colorless to pale yellow liquid |
| Functional Group | Thiol (–SH) |
| Solubility | Miscible with many organic solvents |
Product Features
High Reactivity
The thiol group makes this compound highly reactive, allowing it to participate in esterification, polymer modification, and sulfur-containing compound synthesis.
Versatile Chemical Intermediate
Widely used as a building block for pharmaceuticals, agrochemicals, and specialty chemicals.
Reliable Industrial Performance
Suitable for large-scale chemical manufacturing due to stable chemical properties and consistent purity.
Efficient Synthesis Component
Commonly used in reactions that introduce sulfur functionality into organic molecules.
Main Applications
1. Pharmaceutical Intermediates
Methyl 2-sulfanylacetate is used in the synthesis of various sulfur-containing pharmaceutical intermediates and active compounds.
2. Agrochemical Production
The compound serves as an intermediate in the preparation of certain pesticides and crop protection chemicals.
3. Polymer and Material Modification
The thiol functionality enables its use in polymer modification, specialty resins, and functional materials.
4. Chemical Synthesis
It acts as a key reagent for thiol-based reactions, making it useful in laboratories and industrial organic synthesis.
5. Flavor and Fragrance Research
Certain thiol derivatives derived from this compound are studied for specialty aroma chemistry and advanced formulations.
Typical Specifications
| Parameter | Specification |
|---|---|
| Purity | ≥ 98% |
| Appearance | Clear liquid |
| Water Content | ≤ 0.5% |
| Density | Approx. 1.15 g/cm³ |
| Boiling Point | Approx. 140–145°C |
Specifications may vary depending on industrial requirements.
Packaging and Storage
Packaging Options
25 kg plastic drums
200 kg HDPE drums
Customized packaging available for bulk orders
Storage Conditions
Store in a cool, dry, and well-ventilated place
Keep away from oxidizing agents and strong bases
Ensure containers are tightly sealed
Proper storage helps maintain product stability and shelf life.
Safety and Handling
Methyl 2-sulfanylacetate contains a thiol functional group, which may produce a strong odor. Appropriate safety precautions should be taken when handling this material.
Recommended practices include:
Use protective gloves and safety goggles
Work in well-ventilated areas
Avoid direct skin or eye contact
Follow standard chemical handling procedures
Material Safety Data Sheets (MSDS) are available upon request.
Frequently Asked Questions (FAQs)
1. What is Methyl 2-sulfanylacetate used for?
It is mainly used as a chemical intermediate in pharmaceuticals, agrochemicals, and specialty organic synthesis involving sulfur-containing compounds.
2. Is Methyl 2-sulfanylacetate the same as methyl thioglycolate?
Yes. Methyl thioglycolate is a common synonym for Methyl 2-sulfanylacetate.
3. What industries commonly use this chemical?
Industries that frequently use this compound include pharmaceutical manufacturing, agrochemicals, specialty chemicals, and materials science.
4. How should this product be stored?
It should be stored in sealed containers in a cool, dry, and ventilated environment, away from oxidizing substances.
5. Is bulk supply available?
Yes. Industrial suppliers typically provide drum packaging or customized bulk supply depending on the order quantity.
6. Can technical documents be provided?
Yes. COA, MSDS, and technical specifications can be provided for quality verification and regulatory documentation.
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