Diisopropylcarbodiimide

Product Overview

Diisopropylcarbodiimide (DIC, C₇H₁₄N₂) is a colorless to pale yellow liquid organic compound widely used as a reagent in peptide synthesis, organic synthesis, and chemical research. It is valued for its high reactivity, low racemization, and ability to activate carboxylic acids.

DIC is commonly applied in amide bond formation, esterification reactions, and coupling reactions, making it an essential reagent for pharmaceutical, biochemical, and laboratory applications.

Key Product Identification

• Product Name: Diisopropylcarbodiimide

• Synonyms: DIC, N,N'-Diisopropylcarbodiimide

• Chemical Formula: C₇H₁₄N₂

• CAS Number: 693-62-1

• Molecular Weight: 126.20 g/mol

• HS Code: 29271990

• Appearance: Colorless to pale yellow liquid

• Odor: Mild amine-like odor

Chemical & Physical Properties

Values are typical for reagent-grade material.

Manufacturing & Quality Control

Diisopropylcarbodiimide is produced via dehydration of N,N'-diisopropylurea under controlled conditions. Quality control ensures:

• High purity and minimal by-products

• Consistent reactivity for synthetic applications

• Compliance with laboratory and pharmaceutical-grade standards

Each batch undergoes GC/HPLC assay, water content analysis, and appearance inspection to ensure reliability.

Applications of Diisopropylcarbodiimide

Peptide & Pharmaceutical Synthesis

Used as a coupling reagent in peptide bond formation with minimal racemization, widely applied in drug development and biochemical research.

Organic Synthesis

Facilitates esterification, amidation, and condensation reactions in laboratory and industrial settings.

Biochemical Research

Applied in enzyme modification, protein conjugation, and small molecule synthesis due to its selective reactivity.

Industrial Applications

Used in specialty chemical synthesis and formulation as an intermediate for functionalized compounds.

Packaging & Logistics

• Standard Packaging:

• 250 mL / 500 mL glass bottles

• 1 L / 5 L high-quality HDPE or glass drums

• Bulk Supply: Available under request with secure packaging

• Storage Conditions:

• Store in a cool, dry, and inert atmosphere

• Protect from moisture, acids, and oxidizing agents

• Keep containers tightly sealed and away from heat sources

Safety & Handling

• Highly moisture-sensitive and reactive

• Avoid contact with water, acids, and alcohols

• Use standard laboratory PPE: gloves, goggles, lab coat

• Handle under fume hood for inhalation protection

• Consult the Safety Data Sheet (SDS/MSDS) for detailed safety instructions

Regulatory & Documentation

Available upon request:

• COA (Certificate of Analysis)

• SDS / MSDS

• TDS (Technical Data Sheet)

• Compliance with laboratory, pharmaceutical, and research standards

Why Choose Our Diisopropylcarbodiimide?

• ✔ High purity and reliable batch-to-batch consistency

• ✔ Ideal for peptide synthesis, organic synthesis, and biochemical research

• ✔ Flexible packaging and bulk supply options

• ✔ Export-ready documentation and regulatory support

• ✔ Technical guidance for laboratory and industrial applications

Frequently Asked Questions (FAQ)

Q1: What is Diisopropylcarbodiimide used for?

It is used as a coupling reagent in peptide synthesis, organic synthesis, and biochemical research.

Q2: Is Diisopropylcarbodiimide soluble in water?

No, it reacts with water; it is soluble in organic solvents such as dichloromethane, THF, and toluene.

Q3: Can you provide analytical and regulatory documents?

Yes, COA, SDS, TDS, and compliance certificates are available.

Q4: What is the typical minimum order quantity (MOQ)?

MOQ depends on packaging type and destination; please contact us for details.