Calcium Thioglycolate CAS No. 814-71-1

What Is Calcium Thioglycolate?

Calcium thioglycolate is the calcium salt of thioglycolic acid. It is an organic sulfur compound used primarily as a reducing ingredient in depilatory and selected hair-treatment formulations.

The thioglycolate ion can weaken disulfide bonds in keratin, making hair easier to remove or reshape under controlled formulation conditions.

Calcium Thioglycolate Product Information

Exact appearance, assay and physical properties should be confirmed using the approved specification and batch Certificate of Analysis.

Is CAS 814-71-1 Anhydrous or Hydrated?

CAS 814-71-1 identifies anhydrous calcium thioglycolate. Its molecular formula is C₄H₆CaO₄S₂, with a molecular weight of approximately 222.30 g/mol.

Calcium thioglycolate trihydrate contains three molecules of crystal water and may be sold under different CAS identifiers. Its molecular weight and active content per kilogram are therefore different.

Buyers should confirm the following before ordering:

• Anhydrous or hydrated form

• CAS number shown on the SDS and COA

• Assay calculation basis

• Water or hydration content

• Thioglycolic acid equivalent

• Molecular weight used for formulation calculations

Anhydrous and hydrated grades should not be substituted kilogram-for-kilogram without recalculation.

How Does Calcium Thioglycolate Work?

Hair keratin contains disulfide bonds that contribute to its strength and structure. Under suitable formulation conditions, calcium thioglycolate acts as a reducing agent and weakens these bonds.

This allows the treated hair fiber to soften and break away more easily during depilatory treatment. Its effectiveness depends on the available thioglycolate, finished-product pH, contact time, temperature and other formulation ingredients.

Formulators should therefore evaluate active content, pH, contact time and finished-product safety together.

Main Calcium Thioglycolate Applications

Depilatory Creams and Lotions

Calcium thioglycolate is commonly used as an active reducing ingredient in rinse-off hair-removal creams and lotions.

Hair Waving or Reshaping Products

It may be used in selected professional hair-waving or restructuring formulations where the application is permitted by local cosmetic regulations.

Cosmetic Formulation Research

Used in laboratory studies evaluating keratin reduction, formulation stability, odor, pH and hair-fiber performance.

Selected Industrial Processing

Calcium thioglycolate may also be used in specialized keratin or hide-processing applications where controlled reducing action is required.

Suitability must be confirmed through formulation testing and a finished-product safety assessment.

Which Specifications Should Buyers Compare?

Do not compare supplier prices until the chemical form and assay basis have been confirmed.

Formulation and Regulatory Considerations

Calcium thioglycolate is a functional raw material rather than a finished cosmetic product. The formulator is responsible for determining safe concentration, pH, exposure time, warnings and intended use.

In the European Union, thioglycolic acid and its salts are regulated according to product type, ready-to-use concentration and pH. Specified percentages are calculated as thioglycolic acid rather than simply as the weight of calcium thioglycolate powder.

Requirements vary by market and may change. Buyers should review the current regulations for every destination country before commercializing a finished product.

Packaging, Storage and Handling

Calcium thioglycolate should be supplied in sealed, moisture-resistant packaging suitable for its intended grade.

Store the material tightly closed in a cool, dry and well-ventilated location. Protect it from moisture, excessive heat, acids and oxidizing agents. Metal contamination, especially iron or copper, should be minimized during processing.

Avoid breathing dust and contact with the eyes or skin. Use suitable gloves, eye protection and ventilation, and follow the current Safety Data Sheet.

Why Source Calcium Thioglycolate from AOZUN?

AOZUN supports buyers sourcing calcium thioglycolate for cosmetic formulation and industrial applications.

Available support may include:

• Confirmation of anhydrous or hydrated form

• Grade and application review

• COA and SDS documentation

• Sample evaluation before bulk purchasing

• Packaging and export-logistics options

• Support for recurring commercial orders

Product form, specification, packaging and regulatory documentation are subject to confirmation in the official quotation.

Calcium Thioglycolate FAQ

Is calcium thioglycolate the same as thioglycolic acid?

No. Calcium thioglycolate is the calcium salt of thioglycolic acid. Formulation concentration and regulatory limits may be expressed as thioglycolic acid equivalent.

What is the correct molecular weight for CAS 814-71-1?

The molecular weight of anhydrous calcium thioglycolate, C₄H₆CaO₄S₂, is approximately 222.30 g/mol. Hydrated forms have a higher molecular weight.

Why is iron content important?

Iron contamination can cause discoloration and may affect the appearance or stability of the raw material and finished formulation.

Can calcium thioglycolate be added directly to a depilatory cream?

It should only be incorporated through a controlled formulation process. The finished product requires compatibility, stability, pH, performance and safety testing.

Is calcium thioglycolate permitted in cosmetics?

It is permitted in certain markets and product categories subject to concentration, pH, labelling and use restrictions. Applicable local regulations must be checked before use.

Request a Calcium Thioglycolate Quote

Contact AOZUN with the required chemical form, assay, quantity, packaging, destination market and intended application. Our team will review availability and provide the relevant commercial and technical information.