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4'-Hydroxy-4-biphenylcarbonitrile

Cyanobiphenol is a light yellow to beige crystalline powder with a special bitter almond odor. Cyanobiphenylphenol is soluble in organic solvents such as water, alcohol, and ether, but insoluble in non-polar solvents.
  • 19812-93-2

  • C13H9NO

  • 195.22

  • 427-840-4

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Product Description

4'-Hydroxy-4-biphenylcarbonitrile


Product Overview


4'-Hydroxy-4-biphenylcarbonitrile (C₁₃H₉NO) is a white to off-white crystalline organic compound widely used as a key intermediate in pharmaceutical, polymer, and specialty chemical synthesis. Featuring both a hydroxy group and a nitrile-functionalized biphenyl structure, it is a versatile compound for organic synthesis, drug development, and material science applications.


This compound is valued for its high purity, chemical stability, and reactivity, making it essential for research, industrial, and pharmaceutical applications.




Key Product Identification


  • Product Name: 4'-Hydroxy-4-biphenylcarbonitrile

  • Synonyms: 4-Hydroxy-4'-cyanobiphenyl, p-Hydroxy-biphenyl-4-carbonitrile

  • Chemical Formula: C₁₃H₉NO

  • CAS Number: 19925-27-0

  • Molecular Weight: 195.22 g/mol

  • HS Code: 29241900

  • Appearance: White to off-white crystalline powder

  • Odor: Odorless

  • Solubility: Soluble in organic solvents such as ethanol, acetone, and DMSO; slightly soluble in water




Chemical & Physical Properties


Property Typical Value
Purity ≥ 98%
Melting Point 142 – 145 °C
Density 1.26 g/cm³
Stability Stable under dry and cool conditions; avoid strong oxidizing agents
Reactivity Hydroxy and nitrile groups enable substitution, condensation, and coupling reactions
Storage Store in a cool, dry, well-ventilated area, away from moisture and sunlight



Manufacturing & Quality Control


4'-Hydroxy-4-biphenylcarbonitrile is synthesized through selective organic reactions using biphenyl derivatives under controlled conditions. Quality control ensures:


  • High chemical purity and minimal residual solvents

  • Consistent particle size and crystallinity

  • Compliance with laboratory, pharmaceutical, and industrial chemical standards


Each batch undergoes HPLC/GC assay, melting point verification, and visual inspection to guarantee performance and reliability.




Applications of 4'-Hydroxy-4-biphenylcarbonitrile


Pharmaceutical Industry

  • Intermediate for drug development and medicinal chemistry

  • Used in the synthesis of bioactive molecules, APIs, and heterocyclic compounds


Polymer & Material Science

  • Applied as a monomer or intermediate for specialty polymers and liquid crystals

  • Enhances thermal stability and functional properties in materials


Organic Synthesis & Research

  • Utilized in academic and industrial organic synthesis

  • Serves as a building block for substitution, condensation, and coupling reactions


Specialty Chemicals

  • Used in fine chemical production for functionalized biphenyl derivatives



Packaging & Logistics


  • Standard Packaging:

    • 25 g, 100 g, 500 g, 1 kg powder in sealed amber glass or HDPE containers


  • Bulk Supply: Available upon request


  • Storage Conditions:

    • Store in cool, dry, and well-ventilated conditions

    • Protect from moisture, heat, and direct sunlight

    • Keep containers tightly sealed




Safety & Handling


  • Avoid inhalation, ingestion, and prolonged skin contact; use standard laboratory PPE

  • Handle under fume hood or ventilated area

  • Consult the Safety Data Sheet (SDS/MSDS) for detailed handling, storage, and emergency instructions




Regulatory & Documentation


Available upon request:


  • COA (Certificate of Analysis)

  • SDS / MSDS

  • TDS (Technical Data Sheet)

  • Compliance with laboratory, pharmaceutical, and industrial chemical standards




Why Choose Our 4'-Hydroxy-4-biphenylcarbonitrile?


  • ✔ High purity and consistent batch quality

  • ✔ Ideal for pharmaceuticals, polymer intermediates, and specialty chemicals

  • ✔ Flexible packaging and bulk supply options

  • ✔ Export-ready documentation and regulatory support

  • ✔ Technical guidance for laboratory and industrial applications




Frequently Asked Questions (FAQ)


Q1: What is 4'-Hydroxy-4-biphenylcarbonitrile used for?


It is used as an intermediate in pharmaceuticals, polymers, specialty chemicals, and organic synthesis.


Q2: Is it soluble in water?


It is slightly soluble in water but readily soluble in organic solvents such as ethanol, acetone, and DMSO.


Q3: Can you provide analytical and regulatory documents?


Yes, COA, SDS, TDS, and compliance certificates are available.


Q4: What is the typical minimum order quantity (MOQ)?


MOQ depends on packaging type and destination; please contact us for details.


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